Targeting Bacterial Genomes for Natural Product Discovery
نویسندگان
چکیده
منابع مشابه
Genomics for natural product discovery
The Natural Product Discovery Institute contains a set of more than 30 000 fungal and actinomycete organisms that can be used for natural product discovery. The natural product library contains purified compounds, partially purified column fractions, and crude extracts from natural product-producing organisms. The collection is available for screening. This site describes a roadmap for analysin...
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There has been renewed interests in the exploration of natural products (NPs) for drug discovery, and continuous investigations of the therapeutic claims and mechanisms of traditional and herbal medicines. In-silico methods have been employed for facilitating these studies. These studies and the optimization of in-silico algorithms for NP applications can be facilitated by the quantitative acti...
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Natural products have been and continue to be the source and inspiration for a substantial fraction of human therapeutics. Although the pharmaceutical industry has largely turned its back on natural product discovery efforts, such efforts continue to flourish in academia with promising results. Natural products have traditionally been identified from a top-down perspective, but more recently ge...
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ژورنال
عنوان ژورنال: Trends in Pharmacological Sciences
سال: 2020
ISSN: 0165-6147
DOI: 10.1016/j.tips.2019.11.002